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Allopurinol

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: Aloprim®;Zyloprim®
    • Brand Names: Canada: Alloprin®;Apo-Allopurinol®;Novo-Purol;Zyloprim®
    • Mexican Brand Names: Atisuril;Etindrax;Genozyl;Puribel 300;Unizuric 300;Zyloprim
    • Pharmacologic Category: Antigout Agent;Xanthine Oxidase Inhibitor

    Uses
    • It is used to stop gouty arthritis.
    • It is used to stop gout attacks. It may take 6 weeks to see the full effect.
    • It is used to stop high uric acid levels during chemo.
    • It is used to stop kidney problems caused by gout.
    • It is used to avoid side effects due to fluorouracil.
    • It is used to treat kidney stones.
    • Allopurinol lowers uric acid.

    Dosing

    How to take

    • Take after meals.
    • Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.
    • There is a liquid (suspension) if you cannot swallow pills. Shake well before use.
    • Those who have feeding tubes may also use the liquid. Flush the feeding tube before and after this drug is given.
    • Keep taking this drug even if you are having a gout attack.
    • Shot:
    • It is given as a shot into a vein over a period of time.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.
    • Do not change the dose or stop this drug. Talk with the doctor.

    Storage

    • Store tablets at room temperature.
    • Protect tablets from light.
    • Protect tablets from water. Do not store in a bathroom or kitchen.
    • Store liquid (suspension) in a refrigerator. Throw away any part not used after 2 weeks.
    • The shot will be given to you in a hospital or doctor's office. You will not store it at home.

    Safety



    Warnings

    • Unsafe side effects may happen. This drug cannot be taken while you are taking some other drugs. Check all the drugs you are taking with your doctor.

    Avoid

    • If you have an allergy to allopurinol or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

    Precautions

    • If you have kidney disease, talk with your doctor.
    • If you have liver disease, talk with your doctor.
    • If you are taking a blood thinner, have your blood work checked. Talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Do not take antacids within 6 hours of this drug.
    • Avoid beer, wine, or mixed drinks.
    • Tell your doctor if you are pregnant or plan on getting pregnant.
    • Tell your doctor if you are breast-feeding.

    Side Effects

    • Skin irritation.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Pain when passing urine or blood in urine.
    • Any rash.
    • Health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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